Neurovations

An Intrathecal CRISPR Strategy for Chronic Pain
2021-08-05 17:30 - 18:30 (America/Los_Angeles)
Complimentary Registration

OVERVIEW

Genetic studies have identified in humans key targets pivotal to nociceptive processing. In particular, a hereditary loss-of-function mutation in NaV1.7, a sodium channel protein associated with signaling in nociceptive sensory afferents, leads to insensitivity to pain without other neurodevelopmental alterations.

We investigated targeted epigenetic repression of NaV1.7 in primary afferents via epigenome engineering approaches based on clustered regularly interspaced short palindromic repeats (CRISPR)–dCas9 and zinc finger proteins at the spinal level as a potential treatment for chronic pain.

Dr. Eric Grigsby, MD, MBA is Chief Executive Officer and Founder of Neurovations. For over three decades, Dr. Grigsby has focused his clinical career on academia and private practice. Today, in addition to busy practices, surgery centers, education divisions and labs, Dr. Grigsby guides research and innovation at Neurovations.

Dr Grigsby has been seminally involved in the majority of the interventional devices and therapies used in the field of pain management. He guides start-ups and industry-leading companies through the innovation, discovery and clinical research process which includes access to sites for clinical investigation in pain and neurologic disease.

The Neurovations Education division holds world-class programs and ACCME accredited conferences in Pain and Neuroscience. Additionally, Neurovations Education helps companies and clinicians develop and learn surgical therapies. Dr. Grigsby’s non-profit foundation, HealthRoots, is committed to community health and innovation for underserved patients and communities.

Originally from Knoxville, Tennessee, Dr. Grigsby is a graduate of Brown University with an undergraduate degree in Biology and Economics. He completed medical school at Boston University School of Medicine and residency training in Anesthesiology and Pain Medicine at the Mayo Clinic in Rochester, Minnesota. He received his Master’s in Business Administration in Health Sector Management from Duke University.

Ana Moreno is the founder and CEO of Navega Therapeutics. She obtained her Ph.D. from the Bioengineering Department at UCSD , where she spent the last four years developing the platform that enables Navega’s innovative approach.

NIH Pain Consortium: ESI, NI, and Established Investigators
2021-08-12 12:00 - 13:15
#5 in the NIH Pain Consortium Grant-Mechanism Webinar Series

The goal of this webinar series is to inform the pain research community of funding opportunities and other resources provided by the NIH.

There is no cost for these webinars, but attendees must register in advance.

Register

Spinal Cord Stimulation: How it Works for Chronic Pain and When to Use it
2021-08-25 11:30 - 2021-08-26 00:30
Learn more about Neuropathic Pain Therapeutics Digital Summit

Dr. Eric Grigsby, MD, MBA has devoted his life to advancing the diagnosis and treatment of chronic pain. In 1992, Dr. Eric Grigsby founded the Napa Pain Institute. Over 25 years later, he has grown a single, small clinic into Neurovations- a national patient care, and innovation company that includes medical device and pharmaceutical innovation, clinical research, pain and neuroscience education, and community health through the non-profit Foundation, HealthRoots.

Dr. Grigsby attended elementary and secondary school in his hometown of Knoxville, Tennessee, and received a Bachelor’s Degree in Biology and Economics from Brown University in Providence, Rhode Island. He formed an interest in Pain Management as a career while working at Boston Children’s Hospital in the Department of Orthopedic Surgery.

After graduating from Boston University Medical School in 1984, Dr. Grigsby trained in General Surgery, Anesthesiology, and Pain Management at the Mayo Clinic in Rochester, Minnesota. He was then invited to join the Medical Staff and teach at the Mayo Medical School. He moved to California in 1989 where he established the pain management center at UC Davis and served as Medical Director until 1992. Following his post at UC Davis, Dr. Grigsby established Napa Pain Institute in Napa, California. He partnered with wife Dr. Mary Rocca to create Rocca Family Vineyards, a small family producer of award-winning wines in the Napa Valley.

More recently, Dr. Grigsby completed his Master’s in Business Administration from Duke University’s Fuqua School of Business and has provided consultation in market analysis, strategic positioning, sales, product development, and physician training for industry leaders and early-stage companies. Dr. Grigsby speaks nationally on topics including neuromodulation, non-operative treatment of spinal disorders, the safe use of medications for treatment of pain, and the legal and regulatory issues relating to the proper treatment of patients with chronic illness.

Dr. Grigsby continues to practice as a board-certified Pain Physician and is among the world’s clinical leaders in the field of neuromodulation. As CEO and Founder of Neurovations, his unwavering mission is to inspire hope and to contribute to the health and well-being of patients and communities through integrated clinical practice, research, and education.

28th Annual Napa Pain Conference
2021-08-28 08:00 - 17:00
Improve your care for persons with acute and chronic pain.

Since its founding in 1990 by Dr. Eric J. Grigsby, the Napa Pain Conference has set the bar for quality education, breaking research, and networking. Innovation happens here.

Details Coming Soon!

NIH Pain Consortium: Technology Development/Therapeutic Development
2021-09-09 12:00 - 13:15
#6 in the NIH Pain Consortium Grant-Mechanism Webinar Series

The goal of this webinar series is to inform the pain research community of funding opportunities and other resources provided by the NIH.

There is no cost for these webinars, but attendees must register in advance.

Register

NIH Pain Consortium: Clinical Phased Mechanisms
2021-10-14 12:00 - 13:15
#7 in the NIH Pain Consortium Grant-Mechanism Webinar Series

The goal of this webinar series is to inform the pain research community of funding opportunities and other resources provided by the NIH.

There is no cost for these webinars, but attendees must register in advance.

Register

Mechanisms of Closed-loop SCS: 5 Years of Patient Data
2021-10-21 17:30 - 18:30
Complimentary Registration

Overview

Join Drs. Eric J. Grigsby, John Parker, and Lawrence Poree for a conversation on closed-loop spinal cord stimulation (SCS).

What are evoked compound action potentials (ECAPs)? How are they used to create a closed-loop neuromodulation system? What can continuous monitoring the neural responses tell us about the presence and influence of pharmacological agents?

Additional Resources

Brooker, C., Russo, M., Cousins, M. J., Taylor, N., Holford, L., Martin, R., … & Parker, J. (2021). ECAP‐Controlled Closed‐Loop Spinal Cord Stimulation Efficacy and Opioid Reduction Over 24‐Months: Final Results of the Prospective, Multicenter, Open‐Label Avalon Study. Pain Practice.Heijmans, L., & Joosten, E. A. (2020). Mechanisms and mode of action of spinal cord stimulation in chronic neuropathic pain. Postgraduate medicine, 132(sup3), 17-21.Parker, J., Karantonis, D., & Single, P. (2020). Hypothesis for the mechanism of action of ECAP-controlled closed-loop systems for spinal cord stimulation. Healthcare Technology Letters, 7(3), 76-80.

Speakers:

Dr. Lawrence Poree, MD, PhD. MPH, Clinical Professor, Department of Anesthesia, University of California at San Francisco (UCSF)Dr. Eric J. Grigsby, MD, MBA, Founder & CEO, Neurovations: A Patient Care and Innovation CompanyJohn Parker, PhD, Founder and Chief Science Officer, Saluda Medical

Complimentary Registration

Dr. Eric Grigsby, MD, MBA is Chief Executive Officer and Founder of Neurovations. For over three decades, Dr. Grigsby has focused his clinical career on academia and private practice. Today, in addition to busy practices, surgery centers, education divisions and labs, Dr. Grigsby guides research and innovation at Neurovations.

Dr Grigsby has been seminally involved in the majority of the interventional devices and therapies used in the field of pain management. He guides start-ups and industry-leading companies through the innovation, discovery and clinical research process which includes access to sites for clinical investigation in pain and neurologic disease.

The Neurovations Education division holds world-class programs and ACCME accredited conferences in Pain and Neuroscience. Additionally, Neurovations Education helps companies and clinicians develop and learn surgical therapies. Dr. Grigsby’s non-profit foundation, HealthRoots, is committed to community health and innovation for underserved patients and communities.

Originally from Knoxville, Tennessee, Dr. Grigsby is a graduate of Brown University with an undergraduate degree in Biology and Economics. He completed medical school at Boston University School of Medicine and residency training in Anesthesiology and Pain Medicine at the Mayo Clinic in Rochester, Minnesota. He received his Master’s in Business Administration in Health Sector Management from Duke University.

John Parker, PhD, Founder and Chief Scientific Officer, founded the Implant Systems team at NICTA that developed the closed-loop feedback technology. Dr. Parker has over 20 years of experience in medical devices, including 13 years at Cochlear Limited, where he served in the role of Chief Technology Officer / executive member of the board of directors.

Dr. Parker has experience in working in every aspect of commercialization of R&D, from pure research through to full industrialization. John has an academic background (PhD ANU) and has worked in both Australian and international universities. Has authored numerous scientific publications and patents. He is an ATSE fellow, Harvard business School (PMD) graduate, Docent at the Royal Institute of technology in Stockholm Sweden, ATSE Clunies Ross Medallist (2010) and Adjunct Professor UNSW School of Biomedical Engineering.

Lawrence Poree, MD, PhD, MPH began his neuromodulation career as a basic science researcher at UC Berkeley where he investigated the analgesic properties of CNS hormones as part of his doctoral thesis. He continued his research in neuromodulation at Johns Hopkins University in the department of Biomedical Engineering where he investigated the neural pathways involved in spinal cord stimulation and the sympathetic nervous system. He decided to apply his research to medical practice and enrolled at Stanford University where he earned his medical degree and completed his residency in anesthesia while continuing to conduct research on the analgesic properties of alpha-2 agonists. He then completed an interventional pain fellowship at UCSF.

He founded and served as medical director of a private practice comprehensive pain management clinic for the next 15 years. During this time, he consulted for various neuromodulation companies in the development of novel neuromodulation devices. He returned to academia to head the neuromodulation program at the University Of California at San Francisco Pain Management Center.

For the past 8 years he has served on the North American Neuromodulation Society (NANS) Board of Directors.

NIH Pain Consortium: NIH staff roles in the process and high-level overview of before and after grant submission
2021-12-09 12:00 - 13:15
#8 in the NIH Pain Consortium Grant-Mechanism Webinar Series

The goal of this webinar series is to inform the pain research community of funding opportunities and other resources provided by the NIH.

There is no cost for these webinars, but attendees must register in advance.

Register

NIH Pain Consortium: Preparing/writing the application/submitting the grant
2021-12-13 12:00 - 13:15
#9 in the NIH Pain Consortium Grant-Mechanism Webinar Series

The goal of this webinar series is to inform the pain research community of funding opportunities and other resources provided by the NIH.

There is no cost for these webinars, but attendees must register in advance.

Register

NIH Pain Consortium: How to build a budget
2022-02-10 12:00 - 13:15
#10 in the NIH Pain Consortium Grant-Mechanism Webinar Series

The goal of this webinar series is to inform the pain research community of funding opportunities and other resources provided by the NIH.

There is no cost for these webinars, but attendees must register in advance.

Register

International Neuromodulation Society 15th World Congress
2022-05-21 00:00 - 2022-05-26 23:59
The INS 15th World Congress, themed Neuromodulation: From Scientific Theory to Revolutionary Therapy, will emphasize the field’s transformative force on disease treatment.

Conference Website

The 29th Napa Pain Conference
2022-08-21 08:00 - 17:00
Join the 29th Napa Pain Conference!

Since its founding in 1990 by Dr. Eric J. Grigsby, Neurovations Education has set the bar for quality education, breaking research, and networking. Innovation happens here.

There will be multiple ways to attend the Napa Pain Conference. Earn CME in the beautiful Napa Valley or online with on-demand recordings.

WSSFN 2022: Neuromodulation: Shaping the Future
2022-09-04 08:00 - 2022-09-07 17:00
World Society for Stereotactic and Functional Neurosurgery 2022 | Icheon, Korea

Conference Website

Penney Cowan, "My Journey Through the Maze of Pain"
2022-12-16 14:30
Honoring the Lasting Legacy of the Leaders in our Field

Today’s clinicians, scientists, and researchers are deeply indebted to the seminal thinkers, early advocates for pain management, and scientific innovators whose groundbreaking contributions to our field forged a path for us to follow.

We welcome Penney Cowan to the podium for the 8th lecture honoring the foundational contributions of leaders in pain medicine.

Join the complimentary live stream on Friday, December 16, 2022, at 2:30 PM PST to hear from a legendary advocate and earn CME.

Secure Your Seat

PURPOSE Network Introduction: NIH HEAL Initiative's Coordinating Center for National Pain Scientists (CCNPS)
2023-01-05 10:00 - 11:00
Register Today

This webinar will offer an overview of the upcoming PURPOSE network.

PURPOSE stands for “Positively Uniting Researchers of Pain to Opine, Synthesize, & Engage”, and that is exactly its goal: to connect pain researchers across the continuum of pain research, from all disciplines and at all career stages.

The online PURPOSE Network is a digital platform that will:• Provide a centralized community for research trainees and researchers across the continuum of basic, translational, and clinical research,• Offer ongoing webinars and training opportunities,• Delivery weekly network digests via email,• Enable multidisciplinary collaborations when developing grant applications, and• Aggregate information around pain research, funding opportunities, and the HEAL Initiative

PURPOSE will also host a conference for early-stage pain researchers and NIH-funded mentors in National Harbor, MD, May 11-13, 2023.

NIH HEAL Initiative and Helping to End Addiction Long-term are registered trademarks of the U.S. Department of Health and Human Services.

Kaua'i Pain Conference
2023-03-04 08:00 - 17:00
Kauai Pain Conference

Designed forAll Providers

The Kaua’i Pain Conference is where health care providers, policy makers, administrators and insurers develop interprofessional solutions to the complex challenges of pain management.

Designed for providers of all specialties to improve their understanding of the etiology, assessment, and treatment of pain.

Evaluating and Treating Pain
2023-06-19 08:00 - 2023-06-23 17:00
A significant amount of research has indicated that many, if not all, types of pain are undertreated. Some data indicate that only 25% of patients treated for pain receive adequate relief. In addition, several studies have shown that various pain-relieving techniques may be used inappropriately, which can result in patient harm. This course provides a comprehensive review and update of the basic science and advances in the field of pain medicine.

The faculty includes specialists in many aspects of pain medicine including anesthesiology, neurology, psychiatry and psychology, internal medicine, physical medicine and rehabilitation, orthopedic surgery, interventional radiology and neurosurgery. Participants learn how to diagnose common pain problems and explore various options for treatment of chronic pain, acute pain and cancer-related pain. Pharmacologic, behavioral and interventional treatments of pain will be discussed. Ample time will be spent addressing the role of opioids in the management of pain.

Course Directors

Carol Warfield, MDLowenstein Distinguished Professor of Anesthesia

Thomas Simopoulos, MA, MDAssociate Professor of Anesthesia; Co-Director, Spine Center, Beth Israel Deaconess Medical Center

The 30th Napa Pain Conference
2023-08-17 08:00 - 2023-08-20 17:00 | COPIA, 500 1st Street, Napa, California, 94559, United States
The theme this year is a legacy of innovation. We invite you to partner in this theme with us. Join us as we celebrate 30 years of innovation!

Earn CME in the beautiful Napa Valley, live online, or on-demand.

Neuromodulation: The Science @ Napa Pain Conference
2023-08-18 08:00 - 2023-08-20 17:00
Neuromodulation: The Science Conference joins the Napa Pain Conference August 18-20, 2023.

NTS @ NPC exists to advance research, dissemination of knowledge, and implementation of new findings within neuromodulation and is the foremost meeting addressing the emerging mechanisms of neuromodulation and how these advances shape technology and clinical implementation.

Kaua'i Pain Conference
2024-03-01 08:00 - 2024-03-02 17:00
The comorbidity, co-prescribing, and co-occurrence of disability among persons with chronic pain create greater challenges in managing each condition and reducing impact. Pain cannot be managed in isolation. (Wallace, 2004)

The Kaua’i Pain Conference curriculum addresses biopsychosocial dimensions of pain:

bio – with advances in the basic neuroscience processes of pain

psychological – how the constellation of cognitive processes interacts with neurological signals to influence health and wellness

social – how societal factors influence patient well-being and clinical practice

ROLE OF NEUROMODULATION IN MIGRAINE
2024-06-04 12:00 - 13:00
All Neurology and Pain Management providers, NPs, PAs,CRCs, are invited to join us to learn more about the history of neuromodulation, it’s role in treating Chronic Migraineand to review the exciting upcoming RELIEV-CM2 study.

The RELIEV-CM2 clinical study will investigate the first-ever, head located implantable neuromodulation devicedesigned to treat Chronic Migraine.

The Business of Pain Presents: The Next Big Thing
2024-09-29 08:00 - 17:00
Where Pain Medicine, Science and Business Intersect

Loews Vanderbilt Hotel, Nashville, TN
